GLP injections for weight loss
Wegovy is a semaglutide-based weight loss treatment that mimics the GLP-1 hormone in the body to reduce appetite and decrease cravings.

Wegovy is most effective when combined with a reduced-calorie diet and physical activity.
How Wegovy works
How much weight can I lose with Wegovy?
People on Wegovy can lose up to 15% of their body weight over 12 months.
A study from 2021 followed 1,961 adults living with obesity or overweight with a related medical problem, and were randomly assigned the GLP-1 injections or a placebo.
After 68 weeks, those taking the GLP-1 lost an average of 15.3kg, whereas the placebo group lost an average of 2.6kg.[3]
Wegovy vs Mounjaro for weight loss
Another notable weight loss injection is Mounjaro. While it is frequently compared to Wegovy, some significant differences exist between these two medications.
Wegovy functions as a GLP-1 agonist, which means it mimics the action of the GLP-1 hormone that is naturally released after eating. This mechanism helps to increase feelings of fullness and reduce appetite, leading to decreased food intake and effective weight loss. In contrast, Mounjaro targets GLP-1 receptors and also activates GIP receptors, enhancing its weight loss effects through a dual-action approach.
In clinical trials, people on Wegovy achieved an average weight loss of about 15% over 12 months. This outcome showcases Wegovy's efficacy as a standalone treatment for obesity.
Although there are currently no direct head-to-head trials published comparing these two medications, the existing clinical data suggests that both Wegovy and Mounjaro can effectively support weight management goals. Ultimately, anyone considering these treatments should consult with a healthcare professional to determine which option aligns best with their needs and health profiles.
10mg, 12.5mg, 15mg
You gradually increase your dose every 4 weeks, but you don’t necessarily have to increase to the highest dose — some people don’t tolerate the 2.4 mg dose very well.
Your prescriber will advise you on increasing your dose and what strength is best for your maintenance dose.

For most Juniper patients, injecting their own medication is a brand new experience and it’s completely normal to feel nervous or even a little scared.
In this video, we’ll go through the steps together so you feel comfortable and confident administering your medication.
What are the most common side effects of Wegovy?
Like all prescription medications, Wegovy may cause side effects for some people — it doesn’t mean you’re doing anything wrong, it’s simply your body adjusting to the medication.
The most common side effects are usually gastrointestinal (GI) related, namely nausea and vomiting.[3]
These mild side effects are generally most noticeable right after an injection, and can last anywhere from a few days to a couple of weeks. But, the good news is that these should subside as your body becomes used to the weight loss medication.
Juniper's medical team can work with you to adjust your dose or adopt other interventions to manage side effects.
The most common Wegovy side effects include[3]:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach (abdomen) pain
- Headache
- Tiredness (fatigue)
- Upset stomach
- Dizziness
- Bloating
- Burping
- Heartburn
- Nausea
What are the severe side effects of Wegovy?
While there are a number severe side effects associated with Wegovy, these do tend to be rarer. If you experience any of the below symptoms, please contact your healthcare provider.
The severe side effects can include:
- Possible thyroid tumours, including cancer
- Inflammation of your pancreas (pancreatitis)
- Gallbladder problems
- Increased risk of low blood sugar (hypoglycemia)
- Kidney problems
- Allergic reactionsIncreased heart rate
- Depression
- Changes in vision for people with type 2 diabetes
If you experience a severe rash, swelling of your face, lips, tongue or throat; a very rapid heartbeat or trouble breathing or swallowing, please seek immediate medical attention.
How to manage Wegovy side effects
There are a few ways to manage the mild side effects of Wegovy, like nausea.
For starters, try eating bland, low-fat foods like crackers, toast and rice as well as foods that contain water, like soups. When it comes to mealtimes, try to eat slowly and avoid lying down after you eat.[4]
Be sure to contact your healthcare provider if you are experiencing side effects and they’ll be able to advice you on how to treat this.
Who is eligible to use Wegovy?
Wegovy is a prescription medication, which means alongside a prescriber consult, you need to meet certain requirements to be eligible.
These prerequisites are:
- You have a body mass index (BMI) of 30 or more, indicating obesity
- You have a BMI of 27 or higher, categorised as overweight, coupled with at least one weight-related health condition such as high blood pressure or type 2 diabetes
Is Wegovy available via the NHS?
The National Institute for Health and Care Excellence (NICE) has recommended Wegovy for use within the NHS in England for weight management in adults, alongside a reduced-calorie diet and increased physical activity. To be eligible, you must have at least one weight-related comorbidity and a body mass index (BMI) of at least 35.
However, the MHRA’s marketing authorisation allows for a broader range of eligibility through private providers like Juniper. This includes individuals with a BMI of 27 or above if they have a weight-related health condition, or a BMI of 30 or above without any additional conditions.
Who shouldn’t use Wegovy?
Wegovy isn’t suitable for everyone and there are a few medical conditions that also exclude you from using this medication.
Do not use Wegovy if:
- You or a family member have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) [3]
- You have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy
- If you’re pregnant or breastfeeding[3]
For more information, please reach out to your healthcare provider.
How does Juniper pricing work?
The cost of the Weight Reset Programme varies depending on the medication and dosage you are prescribed.
You will be charged every 4 weeks, with each delivery containing 4 weekly doses of the medication.
(0.25mg)
(0.5mg)
(0.5mg)
(1.7mg)
(2.4mg)
(2.5mg)
(5mg)
(7.5mg)
(10mg)
(12.5mg)
(15mg)
What’s included in the price?
Prescription medication available in all strengths, supply guaranteed
Access to Juniper doctors whenever you need, working closing to provide appropriate dosages throughout your journey
Unlimited support from dietitians to guide you through the programme, one meal at a time
Strength & cardio programme designed for muscle maintenance on weight loss medication
Hundreds of protein-packed recipes designed for patients on Wegovy & Mounjaro
Bluetooth digital scale
Free delivery, so you can save time time by receiving your medication when you need it
Why do I need to pay before I speak with a prescriber?
After you have submitted your quiz, you will be asked to pay to reserve the spot in the programme. If you are approved and decide to continue with the programme, this payment covers the cost of the first month of the programme. If you are ineligible for the medication or change your mind during the consultation process, you will be refunded in full within 1-2 business days.
What if I change my mind during the consultation? Or I’m ineligible?
Once you've taken the quiz, one of our GPhC-registered prescribers will review your answers. They will reach out with any follow-up questions, and you will upload images for the prescriber to determine your eligibility for the programme.
FAQs
Using Wegovy
Kevin Joshua
Kevin Joshua is Juniper’s Clinical Lead and Superintendent Pharmacist. In his role, he designs and delivers specialised support services to help patients access care beyond what the NHS can provide, with a particular focus on weight management and a keen interest in menopause support.
Passionate about achieving the best health and wellbeing outcomes for patients, Kevin is dedicated to delivering a service where every patient feels valued and safe.